Scientific department
BMS

CITHEFOR - Therapeutic targets and preclinical drug evaluation

Therapeutic targets and preclinical drug evaluation research unit (CITHEFOR) develops new therapeutic strategies in the context of vascular diseases (treatment of stroke, prevention of atherosclerosis and restenosis). Its strategy is based on the sustained and controlled release (physiological concentration) of nitrogen monoxide (NO), to optimize its beneficial protective effects at the vascular level.

DCAC - Acute and chronic cardiovascular deficiency

DevAH - Development, adaptation and handicap

Development, adaptation and handicap research unit (DevAH) develops fundamental, applied and clinical research in the sensorimotor and respiratory fields: studies of integrated functions and regulations during development, studies of developmental abnormalities leading to motor or respiratory handicaps.

IADI - Diagnostic and interventional adaptive imaging

Diagnostic and interventional adaptive imaging research unit (IADI) develops techniques and methods to improve adaptive imaging, which consists of taking into account the physiological movements of the patient and/or his organs in order to integrate them into the image acquisition, reconstruction and processing processes. The goal is to improve the imaging of moving organs for diagnosis and understanding of their functioning. It intervenes in very different fields such as the physics of MRI (Magnetic Resonance Imaging) image acquisition, signal and image processing, methodology and clinical validations. Its field of application is cardiac, pulmonary, renal, hepatic and cerebral imaging.

IBSLor - Engineering, biology, health in Lorraine

The mixed service unit Engineering, Biology, Health in Lorraine (IBSLor) provides the scientific community with state-of-the-art technological equipment and unique know-how in the fields of biophysics and structural biology, cytometry, epitranscriptomics, genomics and sequencing, imaging, and proteomics. The core facilities are open to all users belonging to the BMS cluster, the University of Lorraine, as well as to the academic world and to external industrialists.

IGE-PCV - Gene environment interactions in cardio-vascular pathophysiology

Gene environment interactions in cardio-vascular pathophysiology research unit (IGE-PCV) is dedicated to the determination of the respective share of genetic and environmental factors (including dietary habits and physical activity) influencing the predisposition to chronic pathologies as well as their interactions. For many years, research has focused on the epidemiological study of cardiovascular diseases, the second leading cause of death in France after cancer.

IMoPA - Molecular engineering and joint pathophysiology

Molecular engineering and joint pathophysiology research unit (IMoPA) is structured into six teams. The research topics covered include a variety of expertise enabling studies to be carried out at the molecular, structural, cellular or integrated levels. They are completed by a multidisciplinary translational research in cell therapy, regenerative medicine and in the field of chronic inflammatory diseases, which extends from the production of stem or immune cells of clinical grade for antiviral or anti-transplantation purposes, to the design of substitute biomaterials for vascular or osteoarticular purposes and their characterization by imaging techniques, through the study of physiopathological factors linking inflammatory joint and digestive diseases.

INSPIIRE - Interdisciplinarité en Santé Publique, Interventions & Instruments de Mesures Complexes

Adaptation, measurement and evaluation in health - Interdisciplinary approaches research unit (APEMAC) works on four cross-cutting themes co-constructed and piloted by researchers from the Complex Measures and Interventions in Health (MICS) and Adaptation, Health Behavior and Psychological Management (EPSAM) teams.
Thematized research focuses on the areas of health prevention and promotion, medical and psychotherapeutic care, and the organisation of health services and pathways.
A methodological reflection is organized in a theme Concepts and methods around complex interventions in health on one hand, and perceived health measures on the other hand.

NGERE - Nutrition-genetics and exposure to environmental risks

Nutrition-genetics and exposure to environmental risks research unit (NGERE) focuses its research activity on the trajectories of normal and pathological aging, in particular in relation to the metabolism of monocarbons and micronutrients and the epigenome. We are developing preclinical and clinical studies on innovative treatments for rare diseases, steatohepatitis and chronic inflammatory bowel diseases, in collaboration with the companies PAT, Inotrem, Aprofol.
The scientific project of the unit is based on the strong involvement of the unit in the regional, national and international environment, in the FHU ARRIMAGE, the impact program entitled GEENAGE of the I-Site LUE Lorraine University of Excellence, the regional project OMAGE and three international projects: NuttMed, DIFAMEM and Euronanomed

SIMPA - Stress, immunity, pathogens

Stress, immunity, pathogens research unit (SIMPA) is the result of the collaboration of immunologists, microbiologists and neurobiologists who study together the impact of chronic socio-environmental or gravitational stresses on the immune system, the nervous system and microbiota. Our work takes advantage of the national and international recognition acquired in space immunology by the unit, of the complementarity of our approaches and knowledge, and of a very favorable scientific environment.
Our research has an applied aim for astronauts but also a wider societal aim since stress is omnipresent in our society.